John Oswald is a Demi, a human capable of using incredible powers. He is also an agent for World Police, an international security organisation. On their instruction, he is sent to the Japanese village, Tomishogo to investigate suspicious happenings. Unexpectedly, a massive explosion from an abandoned chemical plant rocks the city. Dozens die in the blast, and people across the town begin to get sick. Even stranger, those who survive the sickness become Demi like Oswald. Only these Demi are in a constant state of delirium, unable to distinguish between friend and foe.
In an attempt to contain the sickness, and knowledge of Demi, the Japanese government quarantines the town, preventing news crews and rescue operations from entering. Oswald is now cut off from the World Police. While desperately trying to survive in this terrifying environment, he meets a nine year old girl who's mother died of the sickness. The girl is trying to find her father, a seemingly powerful man who has arranged for the girl to be evacuated. But she is unable to make it to the rendezvous point on her own. Oswald and the girl begin to make the treacherous to what they hope will be an escape.
However, Moka Shiro, leader of the elite military division CMYK1, has plans of her own. She knows a dark secret about the girl, and intends to exploit it for the good of the nation―and her own sick pleasure.
These are the last days of Tomishogo. The events which take place here will change the course of human history.
Art, Character Designs, Original Idea - Enrique Carmena
Producer, Editor - Shoji Amasawa
Programmer, QA - Reika Aoyama
OST - Greyberry
Sound Effects - Seiji Amasawa
ED 'Third World War' - Sayuri Maebara